Basic information of Ccl2 :
| Official Symbol of Gene | Ccl2 |
| Species | Rattus norvegicus |
| Entrez Gene ID | 3645 |
| Official Full Name | C-C motif chemokine ligand 2 |
| Also known as | MCP-1; Scya2; Sigje |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSRNOG00000007159 AllianceGenome:RGD:3645 |
| Map Location | 10q26 |
Sample information of multiple sclerosis:
| Detected Sample | spinal cord |
| Sample Detail | N/A |
| Detected Method | Western Blotting |
| Disease | EAE |
| Disease subtype | N/A |
| Population | Male Lewis rats |
| Sample Size | n = 3 mice group |
Literature information of multiple sclerosis :
| Pubmed ID | 8450228 |
| Year | 1993 |
| Title | Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Macrophage chemotactic factor-1 protein was demonstrated by Western blot in the central nervous system at the height of clinical disease |
| Mechanism/Pathway | within the CNS, the production of factors that recruit macrophages from the periphery into the spinal cord and lead to the expansion and activation of these cells are an important component of the encephalitogenic process. |
