Basic information of Il10 :
| Official Symbol of Gene | Il10 |
| Species | Mus musculus |
| Entrez Gene ID | 96537 |
| Official Full Name | interleukin 10 |
| Also known as | CSIF; If2a; Il-10 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000016529 AllianceGenome:MGI:96537 |
| Map Location | 1 E4; 1 56.89 cM |
Sample information of multiple sclerosis:
| Detected Sample | spleen |
| Sample Detail | N/A |
| Detected Method | Cytokine analysis |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL/6 |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 33565605 |
| Year | 2021 |
| Title | Regulation of EAE by spontaneously generated IL-10-secreting regulatory T cells in HLA-DR15/TCR.Ob1A12 double transgenic mice |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | These mice were found to express large numbers of IL-10-secreting splenocytes as early as 4 weeks of age |
| Mechanism/Pathway | Further investigation of this phenomenon, particularly of the failure to develop spontaneous EAE early, is reported in the present paper |
