Basic information of Hmox1 :
| Official Symbol of Gene | Hmox1 |
| Species | Rattus norvegicus |
| Entrez Gene ID | 2806 |
| Official Full Name | heme oxygenase 1 |
| Also known as | Ho1; Heox; Hmox; Ho-1; HEOXG; hsp32 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSRNOG00000014117 AllianceGenome:RGD:2806 |
| Map Location | 19p11 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | ABC |
| Disease | EAE |
| Disease subtype | N/A |
| Population | Wistar rats |
| Sample Size | n = 3 mice group |
Literature information of multiple sclerosis :
| Pubmed ID | 15497037 |
| Year | 2004 |
| Title | [Dynamic changes of heme oxygenase-1 protein and mRNA in the brains of rats with experimental allergic encephalomyelitis] |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | The results showed that the levels of HO-1 mRNA and its protein expression were very low in the brains of the control group, whereas they were enhanced gradually with pathological course in the brain and onsets of symptoms, signs of EAE.The levels of HO-1 mRNA and its protein expression were lowered gradually on day 21, which were in parallel with the severities of symptoms and signs of EAE |
| Mechanism/Pathway | Antioxidant effect |
