Basic information of Cxcl13 :
| Official Symbol of Gene | Cxcl13 |
| Species | Mus musculus |
| Entrez Gene ID | 1888499 |
| Official Full Name | chemokine (C-X-C motif) ligand 13 |
| Also known as | BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000023078 AllianceGenome:MGI:1888499 |
| Map Location | 5; 5 E3 |
Sample information of multiple sclerosis:
| Detected Sample | spinal cord |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | EAEã€TMEV-IDD |
| Disease subtype | R-EAEã€TMEV-IDD |
| Population | SJL/J mice |
| Sample Size | n = 84(R-EAE mice group)n = 128(TMEV-IDD mice group) |
Literature information of multiple sclerosis :
| Pubmed ID | 31118079 |
| Year | 2019 |
| Title | Differential neuro-immune patterns in two clinically relevant murine models of multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Phenotypic risk |
| Result | CXCL13 protein levels were significantly higher in TMEV-IDD mice compared to R-EAE and sham mice |
| Mechanism/Pathway | Active cycling between demyelination/remyelination and axonal regeneration in the spinal cord of R-EAE mice but not in the spinal cord of mice in the later stage of TMEV-IDD. |
