Basic information of Ighg1 :
| Official Symbol of Gene | Ighg1 |
| Species | Mus musculus |
| Entrez Gene ID | 96446 |
| Official Full Name | immunoglobulin heavy constant gamma 1 (G1m marker) |
| Also known as | IgG1; Igh-4; VH7183 |
| Gene Type | other |
| dbXrefs | IMGT/GENE-DB:IGHG1; AllianceGenome:MGI:96446 |
| Map Location | 12 F1; 12 62.1 cM |
Sample information of multiple sclerosis:
| Detected Sample | spinal cord |
| Sample Detail | N/A |
| Detected Method | Protein measurements by Luminex |
| Disease | EAEã€TMEV-IDD |
| Disease subtype | R-EAEã€TMEV-IDD |
| Population | SJL/J mice |
| Sample Size | n = 84(R-EAE mice group)n = 128(TMEV-IDD mice group) |
Literature information of multiple sclerosis :
| Pubmed ID | 31118079 |
| Year | 2019 |
| Title | Differential neuro-immune patterns in two clinically relevant murine models of multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Phenotypic risk |
| Result | Levels of IgG1 protein in the spinal cord were significantly higher in TMEV-IDD mice compared with R-EAE mice |
| Mechanism/Pathway | Ig production capacities can be associated with the stage of the disease |
