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Basic information of Bdnf :

Official Symbol of Gene Bdnf
Species Mus musculus
Entrez Gene ID 88145
Official Full Name brain derived neurotrophic factor
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000048482 AllianceGenome:MGI:88145
Map Location 2 E3; 2 56.63 cM

Sample information of multiple sclerosis:

Detected Sample spinal cord
Sample Detail N/A
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population adolescent female Lewis rats
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 22050733
Year 2012
Title The role of dorsal root ganglia activation and brain-derived neurotrophic factor in multiple sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result Experimental autoimmune encephalomyelitis animals showed a significant increase in BDNF expression in the caudal spinal cord
Mechanism/Pathway This corroborates previous studies showing anterograde transport of BDNF along microtubules via transport vesicles