Basic information of Xiap :

Official Symbol of Gene	Xiap
Species	Mus musculus
Entrez Gene ID	107572
Official Full Name	X-linked inhibitor of apoptosis
Also known as	Aipa; Api3; IAP3; MIHA; Birc4; ILP-1; 1110015C02Rik
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000025860 AllianceGenome:MGI:107572
Map Location	X; X A4

Sample information of multiple sclerosis:

Detected Sample	brain
Sample Detail	N/A
Detected Method	Western Blotting
Disease	EAE
Disease subtype	N/A
Population	C57BL/6
Sample Size	n = 3 (ubXIAP mice group)/n = 3 (Wild-type mice group)

Literature information of multiple sclerosis :

Pubmed ID	18687476
Year	2008
Title	Increased X-linked inhibitor of apoptosis protein (XIAP) expression exacerbates experimental autoimmune encephalomyelitis (EAE)

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	High levels of protein expression were detected in the brain
Mechanism/Pathway	Our results demonstrate that compared to WT-littermates, ubXIAP mice display an earlier EAE onset andelevated clinical scores, suggesting that increased XIAP ex-pression renders effector T cells more resistant to apoptoticstimuli