Basic information of Sult1a1 :

Official Symbol of Gene	Sult1a1
Species	Mus musculus
Entrez Gene ID	3767
Official Full Name	sulfotransferase family 1A member 1
Also known as	Stm; Stp1; ASTIV; Mx-ST; PST-1; St1a1; Sult1a3
Gene Type	protein coding
dbXrefs	Ensembl:ENSRNOG00000019342 AllianceGenome:RGD:3767
Map Location	1q36

Sample information of multiple sclerosis:

Detected Sample	spinal cord
Sample Detail	N/A
Detected Method	TaqMan PCR
Disease	EAE
Disease subtype	N/A
Population	C57BL/6
Sample Size	n = 3 (case mice group)n = 3 (control mice group)

Literature information of multiple sclerosis :

Pubmed ID	26141748
Year	2015
Title	Transcript analysis of laser capture microdissected white matter astrocytes and higher phenol sulfotransferase 1A1 expression during autoimmune neuroinflammation

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	The difference in protein expression was not as evident as for mRNA expression, but thick astrocytic processes and white matter astrocytes were more easily detected in EAE mice than in control mice in which most fine astrocytic process appeared weakly labeled
Mechanism/Pathway	astrocytes may have not only altered sex steroid synthesis but also higher estrogen conjugation activity, both potentially leading to lower intracellular concentrations active estrogen