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Basic information of Il7 :

Official Symbol of Gene Il7
Species Mus musculus
Entrez Gene ID 96561
Official Full Name interleukin 7
Also known as Il-7; hlb368; A630026I06Rik
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000040329 AllianceGenome:MGI:96561
Map Location N/A

Sample information of multiple sclerosis:

Detected Sample brain
Sample Detail N/A
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population T cell receptor (TCR)–transgenic B6 mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 21795588
Year 2013
Title IL-7 Promotes TH1 Cell Differentiation and Its Level in Serum Predicts Response to Interferon-β in Multiple Sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result We found that high levels of serum IL-7 predict clinical responsiveness in MS patients undergoing IFN-β therapy.
Mechanism/Pathway IL-7Rα–specific antibody reduced nave and effector memory T cells