Basic information of Cx3cr1 :
| Official Symbol of Gene | Cx3cr1 |
| Species | Mus musculus |
| Entrez Gene ID | 1333815 |
| Official Full Name | chemokine (C-X3-C motif) receptor 1 |
| Also known as | mCX3CR1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000052336 AllianceGenome:MGI:1333815 |
| Map Location | 9; 9 F4 |
Sample information of multiple sclerosis:
| Detected Sample | Dorsal root ganglia (DRG) |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | EAE |
| Disease subtype | N/A |
| Population | Lewis rats |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 24175290 |
| Year | 2013 |
| Title | Elevated Expression of Fractalkine (CX3CL1) and Fractalkine Receptor (CX3CR1) in the Dorsal Root Ganglia and Spinal Cord in Experimental Autoimmune Encephalomyelitis: Implications in Multiple Sclerosis-Induced Neuropathic Pain |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Results revealed significant increases in mRNA and the protein expression of CX3CL1 and CX3CR1 in the dorsal root ganglia (DRG) and spinal cord (SC) 12 days after EAE induction compared to controls. |
| Mechanism/Pathway | we conclude that the changes in CX3CL1 and CX3CR1 expression levels are the direct result of activation of the immune response by CNS-myelin-specific antigens such as MBP |
