Details

Home Details


Basic information of IL4 :

Official Symbol of Gene IL4
Species Homo sapiens
Entrez Gene ID 3565
Official Full Name interleukin 4
Also known as BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Gene Type protein coding
dbXrefs Ensembl:ENSG00000113520 MIM:147780; AllianceGenome:HGNC:6014
Map Location 5q31.1

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail Peripheral blood
Detected Method ELISA
Disease MS
Disease subtype RRMS, SPMS, PPMS
Population N/A
Sample Size 123 female and 43 male patients with MS

Literature information of multiple sclerosis :

Pubmed ID 25173940
Year 2014
Title Tumor necrosis factor beta NcoI polymorphism is associated with inflammatory and metabolic markers in multiple sclerosis patients

Results of multiple sclerosis :

Expression down-regulated
Risk type Disease risk
Result Males carrying the TNFB2/B2 genotype exhibited increased levels of TNF-α, IFN-γ, and IL-17 (p = 0.0326) and decreased levels of IL-4, IL-10, insulin, and HOMA-IR.
Mechanism/Pathway Th2 cytokines