Basic information of IL6 :

Official Symbol of Gene	IL6
Species	Homo sapiens
Entrez Gene ID	3569
Official Full Name	interleukin 6
Also known as	CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000136244 MIM:147620; AllianceGenome:HGNC:6018
Map Location	7p15.3

Sample information of multiple sclerosis:

Detected Sample	serum
Sample Detail	N/A
Detected Method	ELISA
Disease	MS
Disease subtype	normal controls (n = 38) or from patients with RRMS (n = 42) and in PBLs from patients with relapsing multiple sclerosis (n = 25) or remitting multiple sclerosis (n = 17).
Population	N/A
Sample Size	normal controls (n = 38) or from patients with RRMS (n = 42) and in PBLs from patients with relapsing multiple sclerosis (n = 25) or remitting multiple sclerosis (n = 17).

Literature information of multiple sclerosis :

Pubmed ID	25362566
Year	2013
Title	MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	IL6 (p \ 0.01, Fig. 1c) were found to increase with lower miR26a expression in PBLs of patients with RRMS or patients with relapsing MS
Mechanism/Pathway	Using the EAE model system, in vivo silencing of miR26a was found to result in increased expression of Th17-related cytokines and increased severity of EAE, while overexpression of miR26a was found to result in reduced expression of Th17- related cytokines and a milder form of EAE.