Basic information of FOXP3 :

Official Symbol of Gene	FOXP3
Species	Homo sapiens
Entrez Gene ID	50943
Official Full Name	forkhead box P3
Also known as	JM2; AIID; IPEX; PIDX; XPID; DIETER
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000049768 MIM:300292; AllianceGenome:HGNC:6106
Map Location	Xp11.23

Sample information of multiple sclerosis:

Detected Sample	serum
Sample Detail	N/A
Detected Method	ELISA
Disease	MS
Disease subtype	normal controls (n = 38) or from patients with RRMS (n = 42) and in PBLs from patients with relapsing multiple sclerosis (n = 25) or remitting multiple sclerosis (n = 18).
Population	N/A
Sample Size	normal controls (n = 38) or from patients with RRMS (n = 42) and in PBLs from patients with relapsing multiple sclerosis (n = 25) or remitting multiple sclerosis (n = 18).

Literature information of multiple sclerosis :

Pubmed ID	25362566
Year	2013
Title	MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	the Foxp3 gene (p \ 0.05, Fig. 1b) showed the same pattern with miR26a. Using
Mechanism/Pathway	Using the EAE model system, in vivo silencing of miR26a was found to result in increased expression of Th17-related cytokines and increased severity of EAE, while overexpression of miR26a was found to result in reduced expression of Th17- related cytokines and a milder form of EAE.