Basic information of Apoe :
| Official Symbol of Gene | Apoe |
| Species | Mus musculus |
| Entrez Gene ID | 11816 |
| Official Full Name | apolipoprotein E |
| Also known as | Apo-E |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000002985 AllianceGenome:MGI:88057 |
| Map Location | 7 A3; 7 9.94 cM |
Sample information of multiple sclerosis:
| Detected Sample | serum and Spinal cord |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | EAE |
| Disease subtype | NA |
| Population | C57BL/9 |
| Sample Size | n=6 sample |
Literature information of multiple sclerosis :
| Pubmed ID | 26669675 |
| Year | 2015 |
| Title | Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | apoE deficiency ameliorates EAE course in male but not female mice |
| Mechanism/Pathway | As sex hormones modify immunomodulatory apoE functions, they may explain contentious findings. |
