Basic information of IL17A :
| Official Symbol of Gene | IL17A |
| Species | Homo sapiens |
| Entrez Gene ID | 3605 |
| Official Full Name | interleukin 17A |
| Also known as | IL17; CTLA8; IL-17; ILA17; CTLA-8; IL-17A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000112115 MIM:603149; AllianceGenome:HGNC:5981 |
| Map Location | 6p12.2 |
Sample information of multiple sclerosis:
| Detected Sample | CSF |
| Sample Detail | NA |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | MS |
| Population | NA |
| Sample Size | 51MS/20Control |
Literature information of multiple sclerosis :
| Pubmed ID | 34950135 |
| Year | 2021 |
| Title | Identification and Clinical Validation of Key Extracellular Proteins as the Potential Biomarkers in Relapsing-Remitting Multiple Sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | IL17A, IL2, CD44, and IGF1 may be key extracellular proteins in the pathogenesis of MS. IL17A, Del-1, and resolvinD1 may co-regulate the development of MS and Del-1 is a potential biomarker of MS. |
| Mechanism/Pathway | Extracellular proteins are most glycosylated and likely to enter into the body fluid to serve as potential biomarkers. |
