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Basic information of GAS6 :

Official Symbol of Gene GAS6
Species Homo sapiens
Entrez Gene ID 2621
Official Full Name growth arrest specific 6
Also known as AXSF; AXLLG
Gene Type protein coding
dbXrefs Ensembl:ENSG00000183087 MIM:600441; AllianceGenome:HGNC:4168
Map Location N/A

Sample information of multiple sclerosis:

Detected Sample CSF
Sample Detail CIS/RRMS/
Detected Method ELISA
Disease MS
Disease subtype NA
Population NA
Sample Size 65MS/40Health

Literature information of multiple sclerosis :

Pubmed ID 23781120
Year 2013
Title Growth Arrest Specific Gene 6 Protein Concentration in Cerebrospinal Fluid Correlates with Relapse Severity in Multiple Sclerosis

Results of multiple sclerosis :

Expression up-regulation
Risk type Phenotypic risk
Result CSF concentration of Gas6 is inversely correlated with the severity of relapse in RR-MS patients but does not predict the subsequent course of the disease.
Mechanism/Pathway Growth arrest specific gene 6 (Gas6) protein enhances survival of oligodendrocytes and neurons, and it is involved in autoimmunity.