Basic information of CHI3L1 :
| Official Symbol of Gene | CHI3L1 |
| Species | Homo sapiens |
| Entrez Gene ID | 1116 |
| Official Full Name | chitinase 3 like 1 |
| Also known as | GP39; ASRT7; GP-39; YK-40; YKL40; CGP-39; YKL-40; YYL-40; HC-gp39; HCGP-3P; hCGP-39 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000133048 MIM:601525; AllianceGenome:HGNC:1932 |
| Map Location | 1q32.1 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | SPMS/PPMS/RRMS |
| Population | NA |
| Sample Size | 220 MS/57Health |
Literature information of multiple sclerosis :
| Pubmed ID | 22183936 |
| Year | 2012 |
| Title | Chitinase 3-like 1 plasma levels are increased in patients with progressive forms of multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Phenotypic risk |
| Result | Plasma CHI3L1 levels were significantly increased in patients with progressive forms of MS compared with RRMS patients and HC. |
| Mechanism/Pathway | Chitinase 3-like 1 (CHI3L1) is upregulated in a wide variety of inflammatory conditions. Recent studies have pointed to a role of CHI3L1 in multiple sclerosis (MS) pathogenesis. |
