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Basic information of Yap1 :

Official Symbol of Gene Yap1
Species Mus musculus
Entrez Gene ID 22601
Official Full Name yes-associated protein 1
Also known as Yap; Yki; Yap65; Yorkie
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000053110 AllianceGenome:MGI:103262
Map Location 9; 9 A1

Sample information of multiple sclerosis:

Detected Sample optic nerve
Sample Detail N/A
Detected Method Immunohistochemistry(免疫组化)
Disease EAE
Disease subtype N/A
Population C57BL/6
Sample Size 8 cases/8 controls

Literature information of multiple sclerosis :

Pubmed ID 34373754
Year 2021
Title Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result compared with control mice, the expression level of YAP was significantly increased in optic nerve of EAE mice
Mechanism/Pathway TGF-β signaling