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Basic information of C3 :

Official Symbol of Gene C3
Species Mus musculus
Entrez Gene ID 12266
Official Full Name complement component 3
Also known as ASP; Plp; HSE-MSF
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000024164 AllianceGenome:MGI:88227
Map Location 17 D; 17 29.72 cM

Sample information of multiple sclerosis:

Detected Sample post-mortem retinas
Sample Detail N/A
Detected Method immunofluorescence
Disease MS
Disease subtype N/A
Population N/A
Sample Size 4 cases/4 controls

Literature information of multiple sclerosis :

Pubmed ID 34487221
Year 2021
Title Complement component 3 from astrocytes mediates retinal ganglion cell loss during neuroinflammation

Results of multiple sclerosis :

Expression N/A
Risk type Disease risk
Result Across these cases, the MS patients expressed higher levels of C3 in the GCL than the non-MS controls.
Mechanism/Pathway N/A