Basic information of B4galt6 :
| Official Symbol of Gene | B4galt6 |
| Species | Mus musculus |
| Entrez Gene ID | 56386 |
| Official Full Name | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 |
| Also known as | N/A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000056124 AllianceGenome:MGI:1928380 |
| Map Location | 18; 18 A2 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | liquid chromotography and tandem mass spectrometry (LC-MS/MS) |
| Disease | EAE |
| Disease subtype | N/A |
| Population | NOD mice |
| Sample Size | n = 15 (naive and acute) or 20 (chronic) samples per condition |
Literature information of multiple sclerosis :
| Pubmed ID | 25216636 |
| Year | 2014 |
| Title | Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | we detected increased LacCer levels in the CNS during the progressive phase of NOD EAE |
| Mechanism/Pathway | these data suggest that LacCer produced by B4GALT5/6 exacerbates CNS inflammation. |
