Basic information of Il4 :
| Official Symbol of Gene | Il4 |
| Species | Mus musculus |
| Entrez Gene ID | 16189 |
| Official Full Name | interleukin 4 |
| Also known as | Il-4; BSF-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000000869 AllianceGenome:MGI:96556 |
| Map Location | 11 B1.3; 11 31.97 cM |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | N/A |
| Disease | EAE |
| Disease subtype | N/A |
| Population | B10.M mice |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 9541508 |
| Year | 1998 |
| Title | Expression of the human histocompatibility leukocyte antigen DR3 transgene reduces the severity of demyelination in a murine model of multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Disease risk |
| Result | we analyzed cytokine expression in the lesions and also determined whether B10.M mice can respond to peptides derived from the DR3 molecule. Intense staining for IFN-g and IL-4, T helper (TH) 1 and TH2 cytokines, respectively, was found in the lesions of TMEV-infected DR32 mice but not in the DR31 transgenic mice at day 21 after infection. |
| Mechanism/Pathway | N/A |
