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Basic information of Rgcc :

Official Symbol of Gene Rgcc
Species Homo sapiens
Entrez Gene ID 28984
Official Full Name regulator of cell cycle
Also known as RGC32; RGC-32; C13orf15; bA157L14.2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000102760 MIM:610077; AllianceGenome:HGNC:20369
Map Location 13q14.11

Sample information of multiple sclerosis:

Detected Sample brain
Sample Detail N/A
Detected Method Immunohistochemistry
Disease MS
Disease subtype N/A
Population N/A
Sample Size 7 cases/6 controls

Literature information of multiple sclerosis :

Pubmed ID 30006805
Year 2018
Title RGC-32 regulates reactive astrocytosis and extracellular matrix deposition in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Expression up-regulation
Risk type Phenotypic risk
Result RGC-32 and ECM components are expressed in MS lesions
Mechanism/Pathway TGF-β induces the expression of RGC-32 in astrocytes