Basic information of NINJ2 :

Official Symbol of Gene	NINJ2
Species	Homo sapiens
Entrez Gene ID	4815
Official Full Name	ninjurin 2
Also known as	N/A
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000171840 MIM:607297; AllianceGenome:HGNC:7825
Map Location	12p13.33

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	CD14 Microbeads
Detected Method	immunocytochemistry
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	7 healthy controls,7 untreated MS

Literature information of multiple sclerosis :

Pubmed ID	36360183
Year	2022
Title	Involvement of NINJ2 Protein in Inflammation and Blood-Brain Barrier Transmigration of Monocytes in Multiple Sclerosis

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	NINJ2 is Down-Regulated after Pro-Inflammatory Stimulation in Monocytes and in THP-1 Cells.
Mechanism/Pathway	Overall, our results suggest that ninjurin2 could be involved in the transmigration of immune cells into the CNS in pro-inflammatory conditions. Further experiments are needed to elucidate the exact molecular mechanisms.