Basic information of ASIC1 :
| Official Symbol of Gene | ASIC1 |
| Species | Homo sapiens |
| Entrez Gene ID | 41 |
| Official Full Name | acid sensing ion channel subunit 1 |
| Also known as | ASIC; ACCN2; BNaC2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000110881 MIM:602866; AllianceGenome:HGNC:100 |
| Map Location | 12q13.12 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | white matter (corpus callosum and corticospinal tract) and deep grey matter |
| Detected Method | immunocytochemistry |
| Disease | MS |
| Disease subtype | PPMS |
| Population | N/A |
| Sample Size | 14 patients |
Literature information of multiple sclerosis :
| Pubmed ID | 23365093 |
| Year | 2013 |
| Title | Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | In chronic brain lesions of patients with progressive multiple sclerosis, we demonstrate an increased expression of ASIC1 in axons and an association with injury markers within chronic inactive lesions. |
| Mechanism/Pathway | N/A |
