Details

Home Details


Basic information of STAT1 :

Official Symbol of Gene STAT1
Species Homo sapiens
Entrez Gene ID 6772
Official Full Name signal transducer and activator of transcription 1
Also known as CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Gene Type protein coding
dbXrefs Ensembl:ENSG00000115415 MIM:600555; AllianceGenome:HGNC:11362
Map Location 2q32.2

Sample information of multiple sclerosis:

Detected Sample cerebral tissue
Sample Detail astrocytes
Detected Method Western blot
Disease MS
Disease subtype N/A
Population N/A
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 12437583
Year 2002
Title Modulation of astrocyte inducible nitric oxide synthase and cytokine expression by interferon beta is associated with induction and inhibition of interferon gamma-activated sequence binding activity

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result Western blot analysis for total Stat1 and Stat2 proteins was performed at 8 and 24 h poststimulation and show that both IFN-b and IFN-c increase the amounts of total Stat protein expression.
Mechanism/Pathway N/A