Basic information of PPARG :

Official Symbol of Gene	PPARG
Species	Homo sapiens
Entrez Gene ID	5468
Official Full Name	peroxisome proliferator activated receptor gamma
Also known as	GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000132170 MIM:601487; AllianceGenome:HGNC:9236
Map Location	3p25.2

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	N/A
Detected Method	Western blot
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	26 MS and 10 healthy donors

Literature information of multiple sclerosis :

Pubmed ID	16210596
Year	2005
Title	Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	Surprisingly, MS patients exhibited decreased PPAR-gamma levels compared with controls.
Mechanism/Pathway	Differences in PPAR-gamma expression were accompanied by changes in PPAR-gamma DNA-binding activity, as preincubation with pioglitazone increased DNA binding of PPAR-gamma.