Basic information of IGFBP7 :
| Official Symbol of Gene | IGFBP7 |
| Species | Homo sapiens |
| Entrez Gene ID | 3490 |
| Official Full Name | insulin like growth factor binding protein 7 |
| Also known as | AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000163453 MIM:602867; AllianceGenome:HGNC:5476 |
| Map Location | 4q12 |
Sample information of multiple sclerosis:
| Detected Sample | blood,cerebrospinal fluid |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | RRMS,SPMS |
| Population | N/A |
| Sample Size | paired CSF and plasma of 40 patients with MS, CSF of 40 NINCs, and plasma of 40 healthy individuals |
Literature information of multiple sclerosis :
| Pubmed ID | 34489947 |
| Year | 2021 |
| Title | Discovery of Novel Biomarkers for Diagnosing and Predicting the Progression of Multiple Sclerosis Using TMT-Based Quantitative Proteomics |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Compared to NINCs, the level of CSF IGFBP7 was significantly upregulated, and the level of CSF SST was significantly downregulated in the MS group. |
| Mechanism/Pathway | N/A |
