Details

Home Details


Basic information of Ackr3 :

Official Symbol of Gene Ackr3
Species Rattus norvegicus
Entrez Gene ID 84348
Official Full Name atypical chemokine receptor 3
Also known as Rdc1; Cxcr7; Cmkor1
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000019622 AllianceGenome:RGD:620601
Map Location 9q36

Sample information of multiple sclerosis:

Detected Sample spinal cords
Sample Detail N/A
Detected Method Immunostaining and Western Blot
Disease EAE
Disease subtype N/A
Population DA (RT1av1) rats
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 21154415
Year 2010
Title Activation of CXCR7 receptor promotes oligodendroglial cell maturation

Results of multiple sclerosis :

Expression N/A
Risk type Disease risk
Result Of note, in the diseased demyelinating central nervous system, CXCR7 expression is maintained on oligodendroglial cells, whereas CXCR4 could not be detected.
Mechanism/Pathway Our findings suggest that a specific activation of the CXCR7 receptor could provide a means to promote oligodendroglial differentiation in the diseased or injured central nervous system.