Basic information of Prmt5 :

Official Symbol of Gene	Prmt5
Species	Mus musculus
Entrez Gene ID	27374
Official Full Name	protein arginine N-methyltransferase 5
Also known as	Jbp1; Skb1
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000023110 AllianceGenome:MGI:1351645
Map Location	14; 14 C2

Sample information of multiple sclerosis:

Detected Sample	brain
Sample Detail	N/A
Detected Method	flow cytometry and immunoblotting
Disease	EAE
Disease subtype	N/A
Population	SJL/J mice
Sample Size	N/A

Literature information of multiple sclerosis :

Pubmed ID	34168658
Year	2021
Title	PRMT5 Promotes Cyclin E1 and Cell Cycle Progression in CD4 Th1 Cells and Correlates With EAE Severity

Results of multiple sclerosis :

Expression	N/A
Risk type	disease risk
Result	In the SJL mouse relapsing-remitting model of MS, the highest PRMT5 expression in central nervous system-infiltrating cells corresponded to peak and relapse timepoints.
Mechanism/Pathway	These data indicate that PRMT5 promotes G1/S cell cycle progression and suggest that this effect influences disease severity and/or progression in the animal model of MS.