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Basic information of Bax :

Official Symbol of Gene Bax
Species Mus musculus
Entrez Gene ID 12028
Official Full Name BCL2-associated X protein
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000003873 AllianceGenome:MGI:99702
Map Location 7 B3; 7 29.32 Cm

Sample information of multiple sclerosis:

Detected Sample Spinal cords
Sample Detail N/A
Detected Method Western Blot
Disease EAE
Disease subtype N/A
Population C57/bl mice
Sample Size n=40 and 46

Literature information of multiple sclerosis :

Pubmed ID 15050683
Year 2004
Title Bax-ablation attenuates experimental autoimmune encephalomyelitis in mice

Results of multiple sclerosis :

Expression N/A
Risk type disease risk
Result In conclusion, ablation of the bax gene attenuates the severity of MOG-induced EAE and emphasizes the importance of apoptosis in the pathogenesis of EAE and MS.
Mechanism/Pathway In conclusion, ablation of the bax gene attenuates the severity of MOG-induced EAE and emphasizes the importance of apoptosis in the pathogenesis of EAE and MS.