Basic information of Mbp :

Official Symbol of Gene	Mbp
Species	Mus musculus
Entrez Gene ID	17196
Official Full Name	myelin basic protein
Also known as	jve; mld; shi; Hmbpr; golli-mbp
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000041607 AllianceGenome:MGI:96925
Map Location	18 E3; 18 55.84 cM

Sample information of multiple sclerosis:

Detected Sample	spinal cord
Sample Detail	N/A
Detected Method	Northern Blotting
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	n = 5–6 mice group

Literature information of multiple sclerosis :

Pubmed ID	7534359
Year	1994
Title	Insertional Mutagenesis Inducing Hypomyelination in Transgenic Mice

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	The 2-50 mice represent a unique model which will be ideal for investigating the molecular basis of myelin assembly and for developing gene therapy to promote remyelination in conditions such as MS.
Mechanism/Pathway	These mice carry a transgene comprising 1.3 Kb of the mouse myelin basic protein (BMP) promoter conjugated to a fragment containing exons 2 and 3 of the human c-myc gene