Basic information of Tnf :

Official Symbol of Gene	Tnf
Species	Mus musculus
Entrez Gene ID	21926
Official Full Name	tumor necrosis factor
Also known as	DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000024401 AllianceGenome:MGI:104798
Map Location	17 B1; 17 18.59 cM

Sample information of multiple sclerosis:

Detected Sample	spleen
Sample Detail	T cells
Detected Method	ELISA
Disease	EAE
Disease subtype	N/A
Population	C57BL/6 mice
Sample Size	n= 6

Literature information of multiple sclerosis :

Pubmed ID	17254640
Year	2007
Title	Disruption of the beta2-integrin CD11d (alphaDbeta2) gene fails to protect against experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Expression	down-regulated
Risk type	disease risk
Result	In contrast, splenic T cells from CD11d/ mice produced two-fold greater levels of IFN-γ, but lower levels of TNF-α compared to control mice.
Mechanism/Pathway	N/A