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Basic information of Mog :

Official Symbol of Gene Mog
Species Mus musculus
Entrez Gene ID 17441
Official Full Name myelin oligodendrocyte glycoprotein
Also known as B230317G11Rik
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000076439 AllianceGenome:MGI:97435
Map Location 17 B1; 17 19.16 cM

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method ELISA
Disease MS
Disease subtype N/A
Population female A.SW mice
Sample Size n = 5–6 mice group

Literature information of multiple sclerosis :

Pubmed ID 16469392
Year 2005
Title Monoclonal MOG-reactive autoantibody from progressive EAE has the characteristics of a natural antibody

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result Although A strain mice have been reported to have an insertion in BAFF-R, the receptor for BAFF (B cell activation factor from the tumor necrosis factor family), which could explain our results, A.SW mice have no mutations in BAFF-R
Mechanism/Pathway MOG but also other antigens, such as gangliosides, histone, blood, liver and kidney proteins