Basic information of BDNF :
| Official Symbol of Gene | BDNF |
| Species | Homo sapiens |
| Entrez Gene ID | 627 |
| Official Full Name | brain derived neurotrophic factor |
| Also known as | ANON2; BULN2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000176697 MIM:113505; AllianceGenome:HGNC:1033 |
| Map Location | 11p14.1 |
Sample information of multiple sclerosis:
| Detected Sample | Human U251 glioma cells |
| Sample Detail | N/A |
| Detected Method | Western blot |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 27235578 |
| Year | 2016 |
| Title | Title: Elevation of Ser9 phosphorylation of GSK3 is required for HERV-W env-mediated BDNF signaling in human U251 cells |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | These results indicated that phosphorylation of GSK3β at Ser9 might be involved in HERV-W env-induced BDNF expression, and will hopefully improve our understanding of the role of HERV-W env in neurological and psychiatric diseases |
| Mechanism/Pathway | GSK3β signaling pathway in U251 cells |
