Basic information of TREM1 :
| Official Symbol of Gene | TREM1 |
| Species | Homo sapiens |
| Entrez Gene ID | 54210 |
| Official Full Name | triggering receptor expressed on myeloid cells 1 |
| Also known as | CD354; TREM-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000124731 MIM:605085; AllianceGenome:HGNC:17760 |
| Map Location | 6p21.1 |
Sample information of multiple sclerosis:
| Detected Sample | brainã€CSF and plasma tests |
| Sample Detail | N/A |
| Detected Method | Western blotting |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 33881612 |
| Year | 2021 |
| Title | TREM2 expression in the brain and biological fuids in prion diseases |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | sTREM2 in the CSF of cases with Alzheimer’s disease, and multiple sclerosis was not signifcantly altered in our series |
| Mechanism/Pathway | compared to controls, TREM2 is increased in sCJD patient brains at the mRNA and protein levels in a regional and subtype dependent fashion, and expressed in a subpopulation of microglia |
