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Basic information of da :

Official Symbol of Gene da
Species Mus musculus
Entrez Gene ID 13130
Official Full Name dark
Also known as N/A
Gene Type unknown
dbXrefs AllianceGenome:MGI:94856
Map Location chromosome: 7

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method Immunohistochemical analysis
Disease MS
Disease subtype N/A
Population C57BL6/J females
Sample Size n = 5–6 mice group

Literature information of multiple sclerosis :

Pubmed ID 18400855
Year 2008
Title A Subgenomic Segment of Theiler’s Murine Encephalomyelitis Virus RNA Causes Demyelination

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result demonstrate that DA RNA or a DA protein(s) is toxic to myelin-synthesizing cells. This Cre/loxP transgenic system allows for spatially and temporally controlled expression of the viral transgene and is valuable for clarifying nonimmune (and immune) mechanisms of demyelination induced by TMEV as well as other viruses
Mechanism/Pathway Cre/loxP transgenic system