Basic information of Cd4 :
| Official Symbol of Gene | Cd4 |
| Species | Mus musculus |
| Entrez Gene ID | 12504 |
| Official Full Name | CD4 antigen |
| Also known as | L3T4; Ly-4 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000023274 AllianceGenome:MGI:88335 |
| Map Location | 6 F2; 6 59.17 cM |
Sample information of multiple sclerosis:
| Detected Sample | Spinal cords |
| Sample Detail | macrophages |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 11836399 |
| Year | 2002 |
| Title | Chemokine Expression in the Central Nervous System of Mice with a Viral Disease Resembling Multiple Sclerosis: Roles of CD4β and CD8β T Cells and Viral Persistence |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Our observations indicated that chemokine expression in the CNS in this chronic viral disorder was intrinsic to the CNS innate immune response to infection and was not governed by elements of the adaptive immune system. |
| Mechanism/Pathway | resistant B6 animals were rendered TMEV-susceptible by deletion of either CD4or CD8T cells |
