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Basic information of Mog :

Official Symbol of Gene Mog
Species Mus musculus
Entrez Gene ID 17441
Official Full Name myelin oligodendrocyte glycoprotein
Also known as B230317G11Rik
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000076439 AllianceGenome:MGI:97435
Map Location 17 B1; 17 19.16 cM

Sample information of multiple sclerosis:

Detected Sample Peripheral blood
Sample Detail N/A
Detected Method Western blot
Disease EAE
Disease subtype N/A
Population C57BL/6
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 12925695
Year 2003
Title Myelin/oligodendrocyte glycoprotein–deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result This total lack of immune tolerance to MOG in WT C57BL/6 mice may be responsible for the high pathogenicity of the anti-MOG immune response as well as the high susceptibility of most animal strains to MOG-induced EAE
Mechanism/Pathway EAE is transferred to MOG+/+ recipients by either resting or primed T cells from MOG–/– and MOG+/+ mice