Basic information of SPP1 :
| Official Symbol of Gene | SPP1 |
| Species | Homo sapiens |
| Entrez Gene ID | 6696 |
| Official Full Name | secreted phosphoprotein 1 |
| Also known as | OPN; BNSP; BSPI; ETA-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000118785 MIM:166490; AllianceGenome:HGNC:11255 |
| Map Location | 4q22.1 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 425 patients (158 male, 267 female) |
Literature information of multiple sclerosis :
| Pubmed ID | 15885319 |
| Year | 2005 |
| Title | Osteopontin gene haplotypes correlate with multiple sclerosis development and progression |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | These data suggest that OPN genotypes may influence MS development and progression due to their influence on OPN levels |
| Mechanism/Pathway | OPN is a 60-kDa secreted phosphoprotein functioning as a free cytokine in body fluids or as an immobilized extracellular matrix molecule in mineralized tissues |
