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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Mus musculus
Entrez Gene ID 15978
Official Full Name interferon gamma
Also known as Ifg; If2f; IFN-g
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location 10 D2; 10 66.75 cM

Sample information of multiple sclerosis:

Detected Sample peripheral lymphoid organs
Sample Detail Lymph node
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population C57BL/6 mice
Sample Size n=3

Literature information of multiple sclerosis :

Pubmed ID 24463315
Year 2014
Title Developmentally regulated GTP-binding protein 2 ameliorates EAE by suppressing the development of TH17 cells

Results of multiple sclerosis :

Expression down-regulated
Risk type disease risk
Result DRG2 overexpression decreases the TH17 population and expression levels of proinflammatory cytokines in peripheral blood cells.
Mechanism/Pathway Autoantigen-specific TH1 and TH17 lineages have been shown to mediate EAE.