Basic information of Gnmt :

Official Symbol of Gene	Gnmt
Species	Mus musculus
Entrez Gene ID	14711
Official Full Name	glycine N-methyltransferase
Also known as	N/A
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000002769AllianceGenome:MGI:1202304
Map Location	17 22.9 cM; 17 C

Sample information of multiple sclerosis:

Detected Sample	spinal cords
Sample Detail	N/A
Detected Method	ELISA
Disease	EAE
Disease subtype	N/A
Population	C57BL/6 mice
Sample Size	n = 5–6 mice group

Literature information of multiple sclerosis :

Pubmed ID	25535034
Year	2014
Title	Role of Glycine N-Methyltransferase in the Regulation of T-Cell Responses in Experimental Autoimmune Encephalomyelitis

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	In summary, our findings suggest that GNMT is involved in the pathogenesis of EAE and plays a crucial role in the regulation of CD4+ T-cell functions
Mechanism/Pathway	When the T-cell receptor was stimulated, the proliferative capacity and the activation status of mTOR-associated downstream signaling were decreased significantly in Gnmt–/– CD4+ T cells via an IL-2- and CD25-independent manner