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Basic information of ETS1 :

Official Symbol of Gene ETS1
Species Homo sapiens
Entrez Gene ID 2113
Official Full Name ETS proto-oncogene 1, transcription factor
Also known as p54; ETS-1; EWSR2; c-ets-1
Gene Type protein coding
dbXrefs Ensembl:ENSG00000134954 MIM:164720; AllianceGenome:HGNC:3488
Map Location 11q24.3

Sample information of multiple sclerosis:

Detected Sample Peripheral blood、CFS
Sample Detail T Cell
Detected Method ELISA
Disease MS
Disease subtype N/A
Population N/A
Sample Size 33 healthy controlled samples, 36 MS patients during remitting stage and 42 during relapsing stage

Literature information of multiple sclerosis :

Pubmed ID 32633381
Year 2020
Title MiR-1-3p facilitates Th17 differentiation associating with multiple sclerosis via targeting ETS1

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result The study demonstrated the positive role of miR-1-3p in Th17 differentiation associated with MS via targeting ETS1.
Mechanism/Pathway MiR-1-3p overexpression in nave CD4+ T cells promoted the differentiation of Th17 cells by upregulating the level of inflammation-associated markers