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Basic information of Ifnb1 :

Official Symbol of Gene Ifnb1
Species Mus musculus
Entrez Gene ID 15977
Official Full Name interferon beta 1, fibroblast
Also known as Ifb; IFNB; If1da1; IFN-beta
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000048806 AllianceGenome:MGI:107657
Map Location 4 C4; 4 41.91 cM

Sample information of multiple sclerosis:

Detected Sample spleens
Sample Detail N/A
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population Swiss Webster mice
Sample Size 40 cases/6 controls

Literature information of multiple sclerosis :

Pubmed ID 16782409
Year 2006
Title Gene-Based Intramuscular Interferon-B Therapy for Experimental Autoimmune Encephalomyelitis

Results of multiple sclerosis :

Expression up-regulation
Risk type Treatment risk
Result Our results indicate the viability of a convenient and effective gene-based alternative for long-term IFN-B protein therapy in MS.
Mechanism/Pathway sustained elevation in 2V, 5V-OAS mRNA