Basic information of IL1B :
| Official Symbol of Gene | IL1B |
| Species | Homo sapiens |
| Entrez Gene ID | 3553 |
| Official Full Name | interleukin 1 beta |
| Also known as | IL-1; IL1F2; IL1beta; IL1-BETA |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000125538 MIM:147720; AllianceGenome:HGNC:5992 |
| Map Location | 2q14.1 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MSã€EAE |
| Disease subtype | PPMS |
| Population | C57BL6/J mice |
| Sample Size | 58cases/12controls |
Literature information of multiple sclerosis :
| Pubmed ID | 32282893 |
| Year | 2020 |
| Title | NLRP3 inflammasome as prognostic factor and therapeutic target in primary progressive multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Altogether, these results point to a role of IL1B and the NLRP3 inflammasome as prognostic biomarker and potential therapeutic target, respectively, in patients with primary progressive multiple sclerosis. |
| Mechanism/Pathway | NF-jB pathway |
