Basic information of Ifng :

Official Symbol of Gene	Ifng
Species	Mus musculus
Entrez Gene ID	15978
Official Full Name	interferon gamma
Also known as	Ifg; If2f; IFN-g
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location	10 D2; 10 66.75 cM

Sample information of multiple sclerosis:

Detected Sample	Serum
Sample Detail	spleen CD4+ T cells
Detected Method	flow cytometry
Disease	EAE
Disease subtype	N/A
Population	C57BL/6 and CD1 mice
Sample Size	seven mice per condition

Literature information of multiple sclerosis :

Pubmed ID	24868560
Year	2014
Title	Regulatory lymphocytes are key factors in MHC-independent resistance to EAE

Results of multiple sclerosis :

Expression	up-regulated
Risk type	Disease risk
Result	C57BL/6 mice that developed EAE after immunization with MOG3555 experienced a significant increase in the percentage of CD4+ T cells producing IFN-gamma.
Mechanism/Pathway	Upregulation of B and, to a lesser extent, of Treg, is closely associated with MHCindependent resistance to MOG-induced EAE in CD1 mice and with the abrogation of both Th1 and Th17 responses.