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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Mus musculus
Entrez Gene ID 15978
Official Full Name interferon gamma
Also known as Ifg; If2f; IFN-g
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location 10 D2; 10 66.75 cM

Sample information of multiple sclerosis:

Detected Sample Serum
Sample Detail N/A
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population B10 mice
Sample Size three per group

Literature information of multiple sclerosis :

Pubmed ID 12663683
Year 2003
Title HLA class II transgenic mice authenticate restriction of myelin oligodendrocyte glycoprotein-specific immune response implicated in multiple sclerosis pathogenesis

Results of multiple sclerosis :

Expression up-regulated
Risk type Disease risk
Result Cytokine analysis revealed an increase in pro-inˉammatory (IFN g, IL-12 and IL-6) and antiinˉammatory (IL-10) cytokines.
Mechanism/Pathway In most forms of EAE, the Th1 cells or Th1 cytokines promote disease, while Th2 cells or cytokines down-regulate disease.