Basic information of Elavl4 :
| Official Symbol of Gene | Elavl4 |
| Species | Mus musculus |
| Entrez Gene ID | 15572 |
| Official Full Name | ELAV like RNA binding protein 4 |
| Also known as | Hud; Elav; PNEM |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000028546 AllianceGenome:MGI:107427 |
| Map Location | 4 C7; 4 51.42 cM |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | GAP43-expressing cells |
| Detected Method | Western blot |
| Disease | EAE |
| Disease subtype | N/A |
| Population | CB57BL/6 female mice |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 36696009 |
| Year | 2023 |
| Title | Posttranscriptional Regulation of Gene Expression Participates in the Myelin Restoration in Mouse Models of Multiple Sclerosis: Antisense Modulation of HuR and HuD ELAV RNA Binding Protein |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Anti-HuR ASO increased the expression of HuD in GAP43-expressing cells and promoted a HuD-mediated neuroprotective activity in MOG–EAE mice. |
| Mechanism/Pathway | HuR silencing restored basal levels of HuD protein as well as neuroflament H and GAP43. |
