Basic information of Tnf :
| Official Symbol of Gene | Tnf |
| Species | Mus musculus |
| Entrez Gene ID | 21926 |
| Official Full Name | tumor necrosis factor |
| Also known as | DIF; Tnfa; TNF-a; TNFSF2; Tnlg1f; Tnfsf1a; TNFalpha; TNF-alpha |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000024401 AllianceGenome:MGI:104798 |
| Map Location | 17 B1; 17 18.59 cM |
Sample information of multiple sclerosis:
| Detected Sample | blood vessels |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL6 mice |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 19878665 |
| Year | 2010 |
| Title | Transient receptor potential vanilloid 1 agonists as candidates for anti-inflammatory and immunomodulatory agents |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Disease risk |
| Result | SA13353 attenuated cytokine levels, including TNF-α, IL-1β, IL-12p40,IL-17, and IFN-γ |
| Mechanism/Pathway | These results suggest that TRPV1 agonists may act as anti-inflammatory and immunomodulatory agents in vivo in certain inflammatory diseases. |
