Basic information of Il12b :
| Official Symbol of Gene | Il12b |
| Species | Mus musculus |
| Entrez Gene ID | 16160 |
| Official Full Name | interleukin 12b |
| Also known as | p40; Il-12b; Il12p40; Il-12p40 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000004296 AllianceGenome:MGI:96540 |
| Map Location | 11 B1.1; 11 25.94 cM |
Sample information of multiple sclerosis:
| Detected Sample | blood vessels |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL6 mice |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 19878665 |
| Year | 2010 |
| Title | Transient receptor potential vanilloid 1 agonists as candidates for anti-inflammatory and immunomodulatory agents |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Disease risk |
| Result | SA13353 attenuated cytokine levels, including TNF-α, IL-1β, IL-12p40,IL-17, and IFN-γ |
| Mechanism/Pathway | These results suggest that TRPV1 agonists may act as anti-inflammatory and immunomodulatory agents in vivo in certain inflammatory diseases. |
