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Basic information of Il17a :

Official Symbol of Gene Il17a
Species Mus musculus
Entrez Gene ID 16171
Official Full Name interleukin 17A
Also known as Il17; Ctla8; IL-17; Ctla-8; IL-17A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000025929 AllianceGenome:MGI:107364
Map Location 1; 1 A4

Sample information of multiple sclerosis:

Detected Sample blood vessels
Sample Detail N/A
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population C57BL6 mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 19878665
Year 2010
Title Transient receptor potential vanilloid 1 agonists as candidates for anti-inflammatory and immunomodulatory agents

Results of multiple sclerosis :

Expression down-regulated
Risk type Disease risk
Result SA13353 attenuated cytokine levels, including TNF-α, IL-1β, IL-12p40,IL-17, and IFN-γ
Mechanism/Pathway These results suggest that TRPV1 agonists may act as anti-inflammatory and immunomodulatory agents in vivo in certain inflammatory diseases.